One of the deadliest types of disease is cancer. Although with the advancement of science and technology, some of cancer does not have a proper cure. It is as bad as life threatening. Most of cancer we know is detected with the size and type of tumor it produces and it also helps the doctor predict which stage it is in. According to the stage, doctors can start their treatment. But in the case of Chronic Myeloid Leukemia (CML), there is no tumor as it occurs in the bone marrow. On the basis of phases, Chronic Myeloid Leukemia can be divided into 3 categories: chronic, accelerated and blast.
Treatment of Chronic Myeloid Leukemia by phase
We often treat cancer depending on its phase. Likewise, chronic myeloid leukemia is treated according to its phases. The treatments that are done according to the phases are discussed below.
While treating the chronic phase of chronic myeloid leukemia tyrosine kinase inhibitor also known as TKI is used. Some of the drugs like bosutinib, nilotinib, imatinib, and dasatinib is used. Sometimes these drugs don’t work well or work at all. In such cases, it is prescribed to change the drug or increase the dosage. The drug, which is, prescribes after T3151 mutation is developed or all the drugs fail is ponatinib. There are certain side effects to these drugs and the doctors might change it according to how the patient reacts. Allogeneic stem cell transplant is very rarely done to patients in the chronic phase.you can also consult with you doctor and consume generic medicine Veenat 400mg in usa by choosing best online pharmacy
The next stage of chronic myeloid leukemia is the accelerated phase. In this phase, the leukemia cell has the capability of gaining a new gene mutation. Due to this the cell build up faster and also the treatment has very less effect. One of the most commonly used drugs in this phase is Imatinib. Most of the time new drugs such as ponatinib, dasatinib does not work in this phase. For all the patients who are healthy and isn’t old, chemo is first used. Then the doctor proceeds to get allogeneic stem cell transplant done which is the best option.
The last phase of chronic myeloid leukemia in the blast phase. In this phase, the cancer cell starts behaving even weirdly. The symptoms get worse with time and also the blood counts get higher. The patients who are diagnosed with blast phase cannot be cured totally. For them, palliative treatment is used which is known for relieving the symptoms, as cancer cannot be cured. Some of the newer Tyrosine Kinase Inhibitor such as bosutinib, nilotinib and dasatinib are seen to be more effective than imatinib in the blast phase. The patients in the blast phase have the possibility of getting leukemia cell in the spinal cord and also the fluid that surrounds our brain.
The above topic talks about how Chronic Myeloid Leukemia is treated according to its phase. It is best if detected in the early stage as the cure for the last stage i.e., is still not found.